Ageing biology, fasting, NAD, senolytics, sauna, cold and the honest evidence. 14 evidence-based guides, each written in plain English with UK context and real citations.
AGEs are sugar-damaged proteins linked to ageing, diabetes and heart disease. Learn the real mechanism, the honest evidence, and how to lower your burden.
Read guide → Longevity & Healthy AgeingAutophagy is the cell recycling system explained: what it is, how mTOR and AMPK control it, what fasting does, and the honest human evidence vs mouse hype.
Read guide → Longevity & Healthy AgeingSenescent zombie cells and the SASP drive ageing. An honest look at senolytics like dasatinib, quercetin and fisetin: strong mouse data, early human trials.
Read guide → Longevity & Healthy AgeingCold water and ice baths: the real physiology, the honest evidence on mood, metabolism and immunity, the muscle-gain catch, and the serious safety risks.
Read guide → Longevity & Healthy AgeingCompare 16:8, OMAD, 5:2 and alternate-day fasting: what randomised trials show for weight loss and metabolic markers, plus why benefits track calories.
Read guide → Longevity & Healthy AgeingMitochondria make most of your cellular energy. How exercise, cold, heat and supplements like CoQ10 and urolithin A really affect them, evidence-graded here.
Read guide → Longevity & Healthy AgeingNAD+ levels fall with age, and NMN and NR aim to restore them. We separate hype from evidence: what the human trials, sirtuins and safety data really show.
Read guide → Longevity & Healthy AgeingOxidative stress explained honestly: why high-dose antioxidant supplements failed or harmed in major trials, and why food beats pills for your health.
Read guide → Longevity & Healthy AgeingPolyphenols such as resveratrol, quercetin and curcumin: the honest evidence, the bioavailability problem, and why whole foods beat most supplements.
Read guide → Longevity & Healthy AgeingRapamycin and metformin for longevity, the honest evidence: strong mouse data, no human lifespan proof, the TAME trial, real risks, and a sober verdict here.
Read guide → Longevity & Healthy AgeingFrequent sauna use is linked to lower cardiovascular and all-cause mortality in Finnish men. The evidence, mechanisms, frequency, limits and safety, explained.
Read guide → Longevity & Healthy AgeingSpermidine triggers autophagy and is linked to lower mortality, but the one rigorous memory trial was negative. The foods, doses and the honest evidence here.
Read guide → Longevity & Healthy AgeingHow deep sleep may flush waste from the brain through the glymphatic system, the amyloid and Alzheimer's link, the honest caveats, and what genuinely helps.
Read guide → Longevity & Healthy AgeingThe twelve hallmarks of ageing in plain English: what each one is, why they interconnect, and which everyday habits map to which, with an honest verdict here.
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